Inflammation is a vital part of the immune system's response to injury and infection. It is the body's way of signaling the immune system to heal and repair damaged tissue, as well as defend itself against foreign invaders, such as viruses and bacteria. Without inflammation as a physiological response, wounds would fester, and infections could become deadly. However, if the inflammatory process goes on for too long or if the inflammatory response occurs in places where it is not needed, it can become problematic. Chronic inflammation has been linked to certain diseases such as heart disease or stroke, and may also lead to autoimmune disorders, such as rheumatoid arthritis and lupus. But a healthy diet and lifestyle can help keep inflammation under control. Acute inflammation Acute inflammation occurs after a cut on the knee, a sprained ankle or a sore throat. It's a short-term response with localized effects, meaning it works at the precise place where a … [Read more...] about What Is Inflammation?
What is acute and chronic inflammation
Chronic pain has reached epidemic proportions in the U.S. Nearly 25.3 million adults experience pain every day lasting for more than three months, according to a recent meta-analysis by the National Health Institute Survey (NHIS), and they’re significantly more likely as a result to have worse overall health, suffer from more disabilities, and require more medical resources. Making matters worse, chronic pain remains poorly understood and difficult to manage — even prescription painkillers only help about 58 percent of people with long-lasting pain, according to the American Academy of Pain Medicine. But the sobering statistics didn’t dissuade John Gribbin and two longtime partners from founding Curable, a Chicago-based startup that seeks to cure — or at the very least mitigate — chronic pain. “Our mission is to provide access to evidence-based, safe, and effective treatment for chronic pain,” Gribbin said. One of the most debilitating things … [Read more...] about Curable aims to treat chronic pain through mindfulness and meditation
Tim Bergling, the Swedish DJ and electronic dance music producer known as Avicii, suffered from pancreatitis and a number of other serious health conditions in the years before he was found dead Friday at the age of 28. An autopsy report later revealed there was no evidence of foul play. Avicii had in the past suffered acute pancreatitis, in part due to excessive drinking. In 2014, after having his gallbladder and appendix removed, he canceled a series of shows while he tried to recover. The performer announced he was retiring from the road in 2016, though he continued to produce songs and albums. "To me it was something I had to do for my health," he told The Hollywood Reporter of his decision to quit touring. What is pancreatitis? Avicii's death at such a young age left fans with many questions about pancreatitis is and the potential complications that can come with it. Pancreatitis occurs when there is inflammation in the pancreas, an organ located in the … [Read more...] about What is pancreatitis? The condition Avicii suffered from years before death
By Stephen S. HallApr. 19, 2018 , 12:15 PM Nick Henry first experienced the symptoms of kidney disease in 2004, shortly after the 19-year-old had a severe reaction to a spider bite. "I woke up one morning, and I was just swollen from head to toe," he recalls. But doctors managed Henry's disease, allowing him to return to his unusually active lifestyle—including baseball, softball, basketball, flag football, golf, and fishing—in his northeast Louisiana hometown of West Monroe. Shortly after he witnessed the death of his mother in a motor scooter accident in 2012, however, Henry's renal health took a dramatic turn for the worse. "It's almost as if my body went into shock," he says. "Within a couple months, boom, I started swelling up again." That swelling was a sign that his kidneys were no longer working normally. A biopsy confirmed that he had focal segmental glomerulosclerosis (FSGS), a severe form of kidney disease. In FSGS, the kidney's glomeruli—the microscopic … [Read more...] about What’s your risk of kidney disease, heart attack, or diabetes? A single molecule can tell
Cells in the nervous system can "put the brakes" on the immune response to infections in the gut and lungs to prevent excessive inflammation, according to research by Weill Cornell Medicine scientists. This insight may one day lead to new ways to treat diseases caused by unchecked inflammation, such as asthma and inflammatory bowel disease. The study, published March 1 in Science, provides some clues about what might be going wrong in these diseases, which have become more common in industrialized countries, and in helminth infections, which are still a major public health problem in less-industrialized countries. It also may explain how some existing treatments for diseases like asthma work and point to new treatment strategies. "There is a crosstalk between the nervous system and the immune system, and that plays an important role in regulating acute and chronic inflammation," said Dr. David Artis, director of the Jill Roberts Institute for Research in Inflammatory Bowel Disease … [Read more...] about Nervous System Puts the Brakes on Inflammation