SAN DIEGO--(BUSINESS WIRE)--May 21, 2018--Cidara Therapeutics, Inc. (Nasdaq: CDTX), a biotechnology company developing novel anti-infectives including immunotherapies, today announced that it and Rutgers University have been awarded a five-year, $5.5 million partnership grant from the U.S. National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health (NIH), an agency of the United States Department of Health and Human Services.The grant will fund the continued research and development of Cidara’s innovative Cloudbreak™ antibody-drug conjugate (ADC) platform to identify novel immunotherapy agents for the treatment and prevention of serious and life-threatening multi-drug resistant (MDR) Gram-negative bacterial infections in high-risk patient populations. The Cloudbreak immunotherapy platform is a fundamentally new approach for the treatment of infectious disease that, in a single molecule, pairs potent antimicrobials with agents that … [Read more...] about Cidara Therapeutics and Rutgers University Awarded $5.5 Million Grant from NIH to Support Development of Novel Immunotherapy Agents Targeting Multi-drug Resistant Gram-negative Bacterial Infections
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A Soviet-era poison called Novichok was used to poison an ex-Russian spy and his daughter last week in England, U.K. Prime Minister Theresa May told Parliament today (March 12). This announcement shows that U.K. authorities were right to suspect that a type of nerve agent had poisoned the former spy, Sergei Skripal, 66, and his daughter, Yulia, 33, who were found stiff and unconscious on a park bench in Salisbury, England on March 4. Both Sergei Skripal and Yulia Skripal are critically ill and in intensive care. But what is Novichok and how does it affect humans? [5 Lethal Chemical Warfare Agents] Novichok, which means "newcomer" in Russian, is a Soviet-era class of nerve agents that was created in the 1970s and 1980s as an attempt to get around the Chemical Weapons Treaty, according to "Responding to Terrorism: A Medical Handbook," published in 2010. That's because the treaty banned chemical weapons that have a certain chemical structure, and Novichok has a different … [Read more...] about What Is Novichok, the Poison that Nearly Killed a Russian Ex-Spy?
Update at 1:00 p.m. EST: U.K. investigators have announced that Ex-Russian spy Sergei Skripal and his daughter Yulia Skripal were likely poisoned by a nerve agent, according to The Guardian. Nerve agents are highly poisonous chemicals that can interfere with signaling from the nervous system, according to the Centers for Disease Control and Prevention. Both of the Skripals are still in intensive care. It's not yet clear which kind of nerve agent was used or the long-term effects the poison will have on the Skripals if they survive this attack. But nerve agents, including sarin, soman, tabun and VX, can have long-lasting effects. For instance, when the Japanese cult Aum Shinrikyo attacked a man with VX nerve agent in 1995, the man survived but continued to feel numbness in part of his body and was reliant on an oxygen tube more than 20 years after the attack, Live Science previously reported. Live Science published this article (below), at 7:11 a.m. EST today: It's still a … [Read more...] about Ex-Russian Spy and Daughter Attacked With Nerve Agent, Not Radiation
If humans were meant to take attractive selfies, they would be born with 5-foot-long arms. According to a research letter published today (March 1) in the journal JAMA Facial Plastic Surgery, 5 feet (1.5 meters) is the optimal distance for taking portraits that don't distort your facial features. Selfies taken just 12 inches (30 centimeters) away from the face, meanwhile, often result in a forced "funhouse mirror" perspective that can make your nose look up to 30 percent wider than it is, Dr. Boris Paskhover, study co-author and facial plastic surgeon, told Live Science. "For years, I've heard patients and family members say, 'Oh, look at my nose, it looks so big,' when they show me a selfie," Paskhover said."I was always telling my patients, that's not how you really look. I knew that selfies distort how your nose looks. And I wanted to prove it." In their new study, Paskhover and his colleagues at Rutgers New Jersey Medical School and at Stanford University in California … [Read more...] about Selfies Distort Your Face by 30% — And Here’s the Math to Back It Up
Your nose isn’t actually as big as it looks in selfies, says facial plastic surgeon Boris Paskhover. So maybe hold off on that nose job — at least, until you’ve seen a decent portrait photo of yourself. Last year, more than half of plastic surgeons were approached by patients who wanted to look better in selfies, according to a survey by the American Academy of Facial Plastic and Reconstructive Surgery. But selfies don’t actually reflect what people look like in the flesh, says Paskhover, who works at Rutgers New Jersey Medical School. “They take out their phone and they say, ‘Look at this picture, look how big my nose looks,’” he says. “I went out to prove why selfies don’t look like the real person, why they’re distorted.” So he teamed up with a computer scientist to create a model of the average human head. The team calculated how much bigger the nose would appear in a photo taken at selfie distance 12 inches … [Read more...] about Your nose isn’t really as big as it looks in selfies