The researchers have started a small clinical trial to determine the appropriate dose of this virus. While that trial is still in progress, they decided to report on two of the patients who received the highest dose. All of the participants were screened for the presence of antibodies against measles, which could interfere with the treatment. Despite immunization, this wasn't as much of a problem as it might seem, given that both myeloma and the treatments for it interfere with immune function. One patient's list of previous treatments was pretty impressive: … [Read more...] about Measles is the latest virus to be turned into a weapon against cancer
Measles about immunization
PlagueUnlike smallpox, this ancient killer is still with us. Caused by a bacterium carried by fleas, plague has been blamed for decimating societies including 14th-century Europe during the Black Death, when it wiped out roughly a third of the population, including in Basel, Switzerland, depicted in this painting from 1349. The disease comes in three forms, but the best known is bubonic plague, which is marked by buboes, or painfully swollen lymph nodes. Though antibiotics developed in the 1940s can treat the disease, in those who are left untreated, plague can have a fatality rate of 50% to 60%, the WHO said. … [Read more...] about 28 Devastating Infectious Diseases
One is that kids might have healthier respiratory tracts because they've been exposed to less cigarette smoke and air pollution than adults, Pavia said. Another factor seems to be that kids are healthier in general, with fewer chronic health conditions, Johnson said. In both the SARS outbreak of 2003 and the MERS outbreak of 2012, adults with chronic health conditions were at a higher risk of death than adults without co-occurring conditions, she said. These conditions could include anything from diabetes to autoimmune disorders to cardiovascular disease, or even simple obesity. … [Read more...] about Why are children ‘missing’ from coronavirus outbreak cases?
Resistance versus toleranceThe answer may lie in how the super-spreading individual’s immune system handles infection. One “resistance” mechanism involves the body’s immune system fighting off infection to control, if not eliminate, the pathogen. In the ensuing battle between host and pathogen, organ and tissue damage often occurs and these individuals often show symptoms. … [Read more...] about One in Five Superspreaders Trigger Majority of Viral Infections
Cruise ships have also begun denying passengers, with Royal Caribbean announcing Feb. 7 that it will deny entry to "all holders of China, Hong Kong and Macau passports, regardless of residency." It's also barring anyone who has travelled to China, Hong Kong or Macau in the 15 days prior to boarding; and anyone who has come within six feet of someone from China, Hong Kong or Macau 15 days prior; and anyone with fever or low blood oximetry. Norwegian Cruise Line is denying entry to anyone who has been through China, Hong Kong and Macau within 30 days prior to the cruise, and to anyone holding a passport from those places. … [Read more...] about Coronavirus outbreak explained: An American dies in China