WADDL’s SARS-CoV-2 pet test is similar to the human test: It uses the polymerase chain reaction (PCR) to amplify RNA from the virus. Baszler says his team developed it with dozens of archived samples of nasal and throat swabs from cats and dogs collected from the western United States, some of which were seeded with SARS-CoV-2. Though none of these animals had COVID-19, the test was able to pick up the virus in the seeded samples, while not reporting false positives for other coronaviruses. Baszler says the World Health Organization has approved the diagnostic and that WADDL could start to test up to 100 pets per day, if needed. … [Read more...] about Should pets be tested for coronavirus?
Korea testing laboratory
While the point-of-care tests have benefits, they likely won't be a major factor in increasing overall testing rates, Kroll said. Abbott's test, for example, can run a sample in 5 minutes, but that's only one sample. Traditional PCR machines at central labs may take a few hours, but a machine can run large numbers of tests at a time. Many use standard 96-well plates, so they can run 96 samples at once. Thus, a point-of-care test might be able to provide quicker answers to individual patients, but they can]t handle the large numbers of tests needed to get a clearer picture of the pandemic. … [Read more...] about Coronavirus testing is ramping up. Here are the new tests and how they work.
Stanley Plotkin of the University of Pennsylvania, inventor of the current rubella vaccine and a leader in the vaccine field, says a carefully designed “human challenge” trial could offer clear proof of a vaccine’s worth at blinding speed. “We’re talking 2, 3 months,” says Plotkin, who has co-authored a commentary, now being submitted for publication, that describes how this might be ethically done. “People who are faced with a terrifying problem like this one will opt for measures that are unusual. And we have to constantly rethink our biases.” A similar proposal for coronavirus challenge studies was published online today in the Journal of Infectious Diseases. … [Read more...] about Speed coronavirus vaccine testing by deliberately infecting volunteers? Not so fast, some scientists warn
The mice lacking C1q didn’t display any obvious visual abnormalities, Stevens says. But they had too many neural connections in a key relay center of the visual pathway, the lateral geniculate nucleus (LGN), showing that C1q was necessary for synaptic refinement. The protein is virtually absent in the neurons of healthy mice with mature brains, suggesting that it plays only a fleeting role early in brain development. In a mouse model of glaucoma, however—a disease in which neurons of the retina are destroyed—Stevens showed that C1q levels were much higher than normal. The findings, reported in Cell in 2007, “were really novel, and set the stage for the whole field” to take a closer look at the role of the complement in brain development and function, Huang says. … [Read more...] about This woman may know a secret to saving the brain’s synapses
“Huawei has shown resilience by replacing many US components over the course of a single phone-design cycle. Its continued use of Qorvo and Skyworks chips also shows that it’s too difficult to break dependence on US technology,” said Dan Wang, technology analyst at research firm Gavekal Dragonomics. … [Read more...] about Teardown of Huawei flagship phone finds US parts despite blacklisting