The enforcer The judge in the case, US District Judge Edward Davila of the Northern District of California, agreed with the prosecutors. As such, he ordered Holmes to undergo up to 14 hours of psychological testing and psychiatric evaluation by two government-appointed doctors over the course of two consecutive days. Davila also ordered that the government’s evaluation of Holmes be recorded on video—over Holmes’ objections. … [Read more...] about Judge in Theranos fraud case orders 14-hour psychological test for Holmes
High iron reading in blood test
When it doubt, hit it with a sword Bamforth and his colleagues decided that there was only one way to truly understand how well the shield would have held up in combat: they built their own and shot it with arrows. “As the bark of the shield dried and bent into its final shape, we realized how strong it would be. The bark, which had been soft and easy to cut when ‘green’ (wet still from being part of a tree) rapidly stiffened up,” explained Bamforth. “We shot some arrows from a wooden bow and were surprised to see them bouncing off.” … [Read more...] about This 2,400-year-old bark shield took a beating in an Iron Age fight
The presynaptic neuron sends neurotransmitters across the synapse to the postsynaptic neuron, Piomelli said. But the presynaptic neuron can also receive information. When a postsynaptic neuron has fired, it can send a message across the synapse that says, "the neuron I come from has been activated," stop sending neurotransmitters, Piomelli said. It sends this "stop" message in the form of endocannabinoids that bind to a receptor called cannabinoid 1 (CB1). … [Read more...] about How does cannabis get you high?
Normally, most factor VIII is stabilized in the body by another protein, von Willebrand factor (VWF), which also protects the clotting factor from disintegrating. However, VWF sets a cap on factor VIII’s time in the body, limiting its half-life to about 15 hours. When factor VIII is infused, it typically latches on to VWF. But researchers at Sanofi and Sobi, the sponsors of the new study, developed a fusion protein that had one small portion of VWF already fused to it. Their hope was that it would be enough to stabilize the clotting factor and prevent it from binding to the body’s own VWF. “Just part of [VWF] stabilizes factor VIII,” Konkle said. “You don’t need the rest of the protein.” … [Read more...] about New fusion protein treatment holds promise for ‘royal’ blood clotting disorder
The researchers checked the fetal cells for expression of a variety of proteins flaviviruses use to latch on to cells. A protein called AXL was the only one that was present. The researchers went on to show that antibodies that bind to the AXL protein prevented Zika from entering cells. These antibodies had no effect on Dengue and West Nile viruses when they were used to infect other cell types. The antibodies also had no effect on other viruses that can cross the placental barrier, like influenza. … [Read more...] about Zika crosses the placenta by latching on to fetal blood vessels