By discovering the culprit behind decreased blood flow in the brain of people with Alzheimer's, biomedical engineers at Cornell University have made possible promising new therapies for the disease. You know that dizzy feeling you get when, after lying down for an extended period, you stand up a little too quickly? That feeling is caused by a sudden reduction of blood flow to the brain, a reduction of around 30 percent. Now imagine living every minute of every day with that level of decreased blood flow. People with Alzheimer's disease don't have to imagine it. The existence of cerebral blood flow reduction in Alzheimer's patients has been known for decades, but the exact correlation to impaired cognitive function is less understood. "People probably adapt to the decreased blood flow, so that they don't feel dizzy all of the time, but there's clear evidence that it impacts cognitive function," said Chris Schaffer, associate professor of biomedical engineering at Cornell University. A … [Read more...] about Researchers Closer to New Alzheimer’s Therapy With Brain Blood Flow Discovery
Decreased blood flow to the brain
Feelings of sadness or anxiety might be linked to increased "chitchat" between two areas of the brain, a new study suggests. In the study, published today (Nov. 8) in the journal Cell, a group of researchers listened in on electrical conversations in the brain — in other words, the signals that brain regions send to one another. When a person is feeling down, they found, the communication increased between brain cells in two specific regions of the brain involved in memory and emotion. It's unclear whether this increased brain communication is a cause or an effect of a bad mood, the researchers noted. However, the findings allowed them to home in on the part of the brain where the action is. [5 Ways Your Emotions Influence Your World (and Vice Versa)] What is clear, however, is that anxiety, depression and mood have physical manifestations in the brain. "For many patients, it is very important to know that when they are feeling depressed, it is due to something measurable and … [Read more...] about What Does Sadness Look Like in the Brain?
A rapidly progressing “polio-like” illness is leaving children in numerous states paralyzed – and experts aren’t sure what’s causing the kids to fall ill.The rare disease, called Acute Flaccid Myelitis (AFM), causes an “inflammation of spinal cord” that resembles cases of polio from the 20th century, Johns Hopkins associate professor of neurology and pathology Dr. Carlos A. Pardo told the Daily News.Cases of AFM have recently been reported in at least five states: Minnesota, Washington, Illinois, Colorado and Pennsylvania.The exact cause of AFM is unknown — it may be a new virus that some children do not have enough immunity to combat and therefore have a bad reaction where the nervous system fails, or the virus attacks the spinal cord directly.“The CDC found evidence of enterovirus D68 in respiratory samples in approximately 20% of patients affected, and other viruses in another 20%, though in the majority of cases a trigger was … [Read more...] about Everything you need to know about the ‘polio-like’ illness popping up around the U.S.
Here's yet another reason to get your blood pressure under control: High blood pressure later in life may contribute to blood vessel blockages and tangles linked to Alzheimer's disease, new research suggests. Tracking nearly 1,300 older people until they died, scientists found markedly higher risks of one or more brain lesions among those with high systolic blood pressure readings. These lesions were dominated by so-called "infarcts" -- areas of dead tissue prompted by blood supply blockages that can trigger strokes. Normal blood pressure is defined as 120/80 mm/Hg or lower. The top number is known as systolic blood pressure (pressure in vessels during heartbeats), while the lower number is diastolic blood pressure (pressure between beats). Late last year, the American College of Cardiology and American Heart Association changed blood pressure recommendations, defining high blood pressure as 130/80 mm/Hg or higher. "We've known for many decades that higher blood pressure, especially … [Read more...] about High blood pressure threatens the aging brain, study finds
Sponsored content from MD News Published 2:46 pm, Tuesday, April 17, 2018 Photo: San Antonio MD News Image 1of/1 CaptionClose Image 1 of 1 Photo: San Antonio MD News PVA: One of the First to Offer Innovative TCAR Procedure for the Treatment of Carotid Artery Disease 1 / 1 Back to Gallery This minimally invasive technology temporarily reverses blood flow in the brain to prevent devastating strokes. Peripheral Vascular Associates (PVA) is one of the first physician groups in the state to perform an innovative treatment for patients at risk for stroke due to blockages in the neck arteries known as carotid artery disease. The minimally invasive procedure, called transcarotid artery revascularization, or TCAR, utilizes a new FDA-approved neuroprotection system that temporarily reverses blood flow in the artery … [Read more...] about PVA: One of the First to Offer Innovative TCAR Procedure for the Treatment of Carotid Artery Disease