Patients with certain chronic eye diseases, like glaucoma and macular degeneration typically either use inefficient eyedrops, or have to get injections directly into their eyes. A team of researchers wants to replace these with a small patch patients can place on the eye, much like a contact lens. When removed, the patch leaves behind microneedles, which slowly dissolve in the corneal fluid, releasing drugs into the eye as they do. They claim it could make treatments more accessible and less painful for patients, while also providing a more controlled release of the drug. Replacing injections with a patch Getting drugs into the eye is a challenge. The most effective solutions tend to be unpleasant and involve actual injections into the eyeball. If doctors deliver the injection in a less horrifying part of the body, it can take a dangerously high initial dose to ensure that enough of the drug actually reaches the eye. Eye drops tend to wash out, and they’re surprisingly … [Read more...] about Dissolving microneedles could replace injections for chronic eye disease
Chronic eye inflammation
Ocular inflammation uveitis is a serious disease that can destroy eye tissue and cause irreversible blindness. Fortunately, blindness and eye damage can be prevented by suppressing the immune system and treating the disease with corticosteroids, said Sai Chavala, MD, Professor of Pharmacology and Neuroscience and Director of Translational Research at the North Texas Eye Research Institute at UNT Health Science Center. “While corticosteroids are effective in treating inflammation and preventing blindness, they often become intolerable over time,” he said. “There’s a risk of systemic side effects such as glucose intolerance, hypertension and osteoporosis with oral steroids.” Treating with intraocular steroids reduces the systemic adverse effects. But this treatment can cause vision loss due to the development of a cataract or steroid-induced glaucoma. But a class of drugs known as MDM2 inhibitors could potentially be a promising new treatment for … [Read more...] about Promising Steroid Treatment for Disease that Destroys Eye Tissue
Jen Skerritt and Craig Giammona Bloomberg News Published 4:56 PM EDT Sep 17, 2018 Coca-Cola Co. said it’s eyeing the cannabis drinks market, becoming the latest beverage company to tap into surging demand for marijuana products as traditional sales slow. The Atlanta-based soft drinks maker says it’s monitoring the nascent industry and is interested in drinks infused with CBD – the non-psychoactive ingredient in marijuana that treats pain but doesn’t get you high. It is in talks with Canadian marijuana producer Aurora Cannabis to develop the beverages, according to a report from BNN Bloomberg Television. “We are closely watching the growth of non-psychoactive CBD as an ingredient in functional wellness beverages around the world,” Coca-Cola spokesman Kent Landers said in an emailed statement to Bloomberg News. “The space is evolving quickly. No decisions have been made at this time.” Landers declined to comment on Aurora. … [Read more...] about Coca-Cola is eyeing the cannabis market
Fat is so often seen as the enemy — something to avoid or lose. But fat is also a crucial component of the body. Without it, humans would freeze. Our nerves, uninsulated, would jangle with crisscrossed communications. We'd be unable to store crucial supplies of certain vitamins, or have a functioning immune system. On a cellular level, fats make the membranes that surround cells possible and act as messengers that bind to proteins and enable various reactions. With that in mind, the humble fat cell seems a bit miraculous. Adipocytes, as they're properly known, are the cells that store excess lipids, the molecules that include fats and related substances. Adipocytes were once thought to be rather dull sacks of energy, but the past few decades of research have revealed that they have a lot to do in the body, from regulating nutrients to releasing hormones that influence blood pressure, thyroid function and even reproduction. [What Is Cellulite?] Anatomy of fat Under a … [Read more...] about What’s in a Fat Cell?
The reproductive system is a collection of internal and external organs — in both males and females — that work together for the purpose of procreating, according to the Cleveland Clinic. Due to its vital role in the survival of the species, many scientists argue that the reproductive system is among the most important systems in the entire body. How reproductive systems work The male reproductive system consists of two major parts: the testes, where sperm are produced, and the penis, according to Merck Manuals. The penis and urethra belong to both the urinary and reproductive systems in males. The testes are carried in an external pouch known as the scrotum, where they normally remain slightly cooler than body temperature to facilitate sperm production. The external structures of the female reproductive system include the clitoris, labia minora, labia majora and Bartholin's glands, according to the Cleveland Clinic. The major internal organs of the female … [Read more...] about Reproductive System: Facts, Functions & Diseases