Sandra G. Boodman, The Washington Post Published 10:03 am PDT, Saturday, April 20, 2019 FILE PHOTO: Late stage skin ulcers in a patient with diffuse lepromatous leprosy, a severe potentially lethal form of leprosy. FILE PHOTO: Late stage skin ulcers in a patient with diffuse lepromatous leprosy, a severe potentially lethal form of leprosy. Photo: MD Anderson Cancer Center Photo: MD Anderson Cancer Center Image 1 of / 42 Caption Close Image 1 of 42 FILE PHOTO: Late stage skin ulcers in a patient with diffuse lepromatous leprosy, a severe potentially lethal form of leprosy. FILE PHOTO: Late stage skin ulcers in a patient with diffuse lepromatous leprosy, a severe potentially lethal form of leprosy. Photo: MD Anderson … [Read more...] about For three years her skin ulcers and pain would flare, then vanish, stumping doctors. Her daughter, a nurse, finally figured it out.
Chronic eye inflammation
Patients with certain chronic eye diseases, like glaucoma and macular degeneration typically either use inefficient eyedrops, or have to get injections directly into their eyes. A team of researchers wants to replace these with a small patch patients can place on the eye, much like a contact lens. When removed, the patch leaves behind microneedles, which slowly dissolve in the corneal fluid, releasing drugs into the eye as they do. They claim it could make treatments more accessible and less painful for patients, while also providing a more controlled release of the drug. Replacing injections with a patch Getting drugs into the eye is a challenge. The most effective solutions tend to be unpleasant and involve actual injections into the eyeball. If doctors deliver the injection in a less horrifying part of the body, it can take a dangerously high initial dose to ensure that enough of the drug actually reaches the eye. Eye drops tend to wash out, and they’re surprisingly … [Read more...] about Dissolving microneedles could replace injections for chronic eye disease
Ocular inflammation uveitis is a serious disease that can destroy eye tissue and cause irreversible blindness. Fortunately, blindness and eye damage can be prevented by suppressing the immune system and treating the disease with corticosteroids, said Sai Chavala, MD, Professor of Pharmacology and Neuroscience and Director of Translational Research at the North Texas Eye Research Institute at UNT Health Science Center. “While corticosteroids are effective in treating inflammation and preventing blindness, they often become intolerable over time,” he said. “There’s a risk of systemic side effects such as glucose intolerance, hypertension and osteoporosis with oral steroids.” Treating with intraocular steroids reduces the systemic adverse effects. But this treatment can cause vision loss due to the development of a cataract or steroid-induced glaucoma. But a class of drugs known as MDM2 inhibitors could potentially be a promising new treatment for … [Read more...] about Promising Steroid Treatment for Disease that Destroys Eye Tissue
A rapidly progressing “polio-like” illness is leaving children in numerous states paralyzed – and experts aren’t sure what’s causing the kids to fall ill.The rare disease, called Acute Flaccid Myelitis (AFM), causes an “inflammation of spinal cord” that resembles cases of polio from the 20th century, Johns Hopkins associate professor of neurology and pathology Dr. Carlos A. Pardo told the Daily News.Cases of AFM have recently been reported in at least five states: Minnesota, Washington, Illinois, Colorado and Pennsylvania.The exact cause of AFM is unknown — it may be a new virus that some children do not have enough immunity to combat and therefore have a bad reaction where the nervous system fails, or the virus attacks the spinal cord directly.“The CDC found evidence of enterovirus D68 in respiratory samples in approximately 20% of patients affected, and other viruses in another 20%, though in the majority of cases a trigger was … [Read more...] about Everything you need to know about the ‘polio-like’ illness popping up around the U.S.
Many people love autumn for the colorful foliage and pumpkin spice, but each year it ushers in another season that is more menacing: cold and flu season, that is. The two illnesses are often lumped together, but there are important distinctions. And when it comes to prevention and treatment, there are plenty of misconceptions that go around. Here, experts separate fact from myth and clear up eight common misconceptions about cold and flu. Myth 1: The flu is just a bad cold While some people may use the words cold and flu interchangeably, they are in fact very different. Flu is a much more serious illness than the common cold. "People need to understand that the flu is serious and can turn deadly," Dr. Melissa Stockwell, associate professor of pediatrics and population and family health at Columbia University Irving Medical Center, told CBS News. "The CDC just released data that last flu season 80,000 Americans died from flu." While some of the symptoms of cold and flu may … [Read more...] about 8 common myths about cold and flu debunked