Focus on precision medicine is encouraging R&D across the cell therapy market with Big Pharma/Bio-Pharma responding through collaborations with small to mid-segment players with niche therapeutic focus, thereby gaining a competitive edge with respect to therapy, technology as well as geographic spread. The market was valued at $2.70 billion in 2017 and is expected to reach $8.21 billion in 2025, growing at a robust compounded annual growth rate (CAGR) of 14.9% between 2017 and 2025. A diverse therapeutic focus, accompanied by rising M&A activities and implementation of advanced manufacturing technologies such as single-use bioreactors, will pave a way for unique cell-gene and stem cell – gene combination therapies. "In addition to collaborations, pharmas are employing a pay-for-performance business model that allows the payer to pay based on the therapeutic outcome of the high-value therapy," said Aarti … [Read more...] about Cell Therapy Market to Grow Beyond Oncology as Big Pharma Expands Investments
Adoptive t cell therapy clinical trials
One Couple’s Tireless Crusade to Stop a Genetic Killer
In retrospect, it might have been a clue. But in early 2010, when Kamni Vallabh first began to complain that her eyesight was failing, there didn’t seem to be much cause for concern. She was 51; maybe middle age was catching up with her. Maybe the harsh western Pennsylvania winter—two record-breaking blizzards in as many weeks—was wearing her down. The previous summer, Kamni had been in good health. She’d single-handedly organized her daughter Sonia’s wedding, 300 guests drinking and dancing in the family’s backyard in Hermitage, a tight-knit former steel town. But by her birthday, that March, it was clear that something was seriously wrong. Once a poet, Kamni could barely string a sentence together. She was distractible, easily confused; when she misplaced the TV remote, she’d look for it in the pantry. Her body, too, was rapidly declining. By May, she couldn’t eat, stand, or bathe herself. She had trouble sleeping and spent her rare … [Read more...] about One Couple’s Tireless Crusade to Stop a Genetic Killer
Cell injections, magnetic chairs and brain implants – Silicon Valley’s wacky quest for IMMORTALITY
SOMEWHERE in Silicon Valley, a man wakes early with the sunrise. Venturing into the kitchen, he pacifies his rumbling belly with a cup of coffee infused with a large knob of grass-fed butter. He’s in the middle of a fast, after all. After a two-hour meditation session, he’s off to spend thousands of dollars on his latest indulgence – stem cell injections. The clinic’s practitioner assures him that removing stem cells from his bone marrow and injecting them into other tissues will rejuvenate them from their fatigued state. He trusts their word, just as he trusts that spraying nicotine into his mouth will give him the benefits of a cigarette without the negative side effects. When he retires for the night, equipped with melatonin tablets and blue light-blocking glasses to ensure his sleep cycle isn’t disturbed, he’s satisfied with the day’s achievements. He’s taken another small step towards his goal. He may be a product of the 21st … [Read more...] about Cell injections, magnetic chairs and brain implants – Silicon Valley’s wacky quest for IMMORTALITY
The Promise—and Heartbreak—of Cancer Genomics
You were a New York artist, Iowa-bred, with a narrow and idiosyncratic range of subjects. You painted bulldogs and cheerleaders, truck stops and mammoth-hunting cavemen. For two decades you inhabited a drowning world, which you nostalgized even as it vanished beneath a tidal swell of money. Its borders were 14th to Canal Street and Broadway to the East River; its capital was the Mars Bar. You were the first to help a friend and last to leave the party, and beloved by your fellow strivers. You were smart, funny, unfailingly courteous: the punk-rock pirate king of the art scene. You loved your life. “But this is wonderful!” you would bellow when a work of art or meal delighted you. You had the best gigs: artist-in-residence at the Museum of Sex; interviewer at Whitehot Magazine; art handler for Manhattan’s galleries, bicycling up and down the island’s streets with a determined expression. But in your late forties you began to feel out of sorts: burdened, … [Read more...] about The Promise—and Heartbreak—of Cancer Genomics
The First Frontier for Medical AI Is the Pathology Lab
Advertisement Editor’s Picks Making Medical AI Trustworthy and Transparent AI Could Provide Moment-by-Moment Nursing for a Hospital’s Sickest Patients “AI Clinician” Makes Treatment Plans for Patients With Sepsis This is how a pathologist could save your life. Imagine you’re coughing up blood, and a chest scan reveals a suspicious mass in your lungs. A surgeon removes a small cylindrical sample from the potential tumor, and the pathologist places very thin slices of the tissue on glass slides. After preserving and staining the tissue, the pathologist peers through a microscope and sees that the cells have the telltale signs of lung cancer. You start treatment before the tumor spreads and grows. And this is how a pathologist could kill you: The expert physician would just have to miss the cancer. Or, more likely, misclassify the cells viewed on the slides as the wrong cancer subtype. Rather than getting a targeted therapy that beats … [Read more...] about The First Frontier for Medical AI Is the Pathology Lab