Areas of hypoxia, or low oxygen in tissue, are hallmarks of fast-growing cancers and of blockages or narrowing in blood vessels, such as stroke or peripheral artery disease. University of Illinois researchers have developed a way to find hypoxic spots noninvasively in real time.The researchers developed an oxygen-sensitive molecular beacon that emits ultrasound signals in response to light, a process called photoacoustic imaging – a less invasive, higher resolution and less costly method than the current clinical standard, which uses radioactive molecules and positron emission tomography scans. In a paper published in Nature Communications, the researchers demonstrated the probe’s ability to image hypoxic tumors and constricted arteries in mice.”We could give a doctor a three-dimensional, real-time view into the tissue to guide surgical procedures and treatment plans,” said chemistry professor Jefferson Chan, the leader of the study. Graduate student Hailey Knox and bioengineering professor Wawrzyniec Lawrence Dobrucki were co-authors of the paper.”The ability to detect this in a way that doesn’t require surgery or doesn’t rely on indirect methods is really powerful, because you can actually see it as it’s developing,” Chan said.Current methods for detecting hypoxia in tissue can only identify chronic hypoxia, and thus cannot help doctors find aggressive… Read full this story
- Coronavirus | Anyone with continuous fever, breathlessness and low oxygen levels to be treated in Andhra Pradesh
- Pregnant amid the pandemic: The highs and lows
- City hospitals face liquid oxygen crisis
- Positivity and mortality rates are low in State, says Jagan
- Does BP's conversion signal the end of Big Oil?
- Brad Pitt keeps a low profile as he dons a flat cap and jeans while running errands in Los Angeles
- When Perfumery Meets Molecular Science
- COVID-19 long-term toll signals billions in healthcare costs ahead
- INSIGHT-Long-term complications of COVID-19 signals billions in healthcare costs ahead
- Blood test could spot brain damage in newborn babies caused by oxygen deprivation and reduce the risk of epilepsy and cerebral palsy
Molecular Beacon Signals Low Oxygen With Ultrasound have 331 words, post on www.eurekalert.org at December 11, 2017. This is cached page on Technology Breaking News. If you want remove this page, please contact us.