The U.S. Food and Drug Administration today expanded the approved use of Adcetris (brentuximab vedotin) injection in combination with chemotherapy for adult patients with certain types of peripheral T-cell lymphoma (PTCL). This is the first FDA approval for treatment of newly diagnosed PTCL, and the agency used a new review program to complete the approval more quickly. “The Real-Time Oncology Review (RTOR) program allows the FDA to access key data prior to the official submission of the application allowing the review team to begin their review earlier and communicate with the sponsor prior to the application’s actual submission,” said Richard Pazdur, MD, director of the FDA’s Oncology Center of Excellence and acting director of the Office of Hematology and Oncology Products. “When the sponsor submits the completed application, the review team will already be familiar with the data and be able to conduct a more efficient, timely and thorough review. RTOR … [Read more...] about FDA Approves First-Line Treatment for Peripheral T-Cell Lymphoma Under New Review Pilot
Samsung Galaxy S10 To Feature ‘Genuinely Bezel-Less’ Display: Report
The Galaxy S10 series of Android flagships will feature "genuinely bezel-less OLED panels," South Korean outlet TheElec reports, citing insiders close to the world's largest smartphone maker. The company's next high-end handsets will lack top bezels and front chins, according to a machine translation of the claims. The devices will also sport two holes drilled into the upper portion of their displays which will house a dual-camera setup, sources claim, adding that the second module in that system will actually be an infrared scanner. While Samsung was unable to integrate the two cameras below the displays of its upcoming Android flagships, it reportedly managed to do so with the proximity and light sensors. The Galaxy S10 line is also expected to once again feature an under-screen LED indicator. The front-facing camera innovation is primarily being attributed to Samsung Electronics Sister Company Samsung Display that internally refers to it as a "Hole in Active Area" solution, insiders … [Read more...] about Samsung Galaxy S10 To Feature ‘Genuinely Bezel-Less’ Display: Report
9900k plus 8 pin CPU connector.
alkatraz333.jhNov 16, 2018, 4:55 PM Okay, so i know the 9900k hits almost 215 watts on a 4.9 frequency. Ive seen a few people hitting 5.0 ghz with only a single 8 pin, but on paper that seems impossible to me, being that an 8 pin only supports up to 235 watts. Does anyone have one, or know for sure if it'll hit 5.0 ghz on a single 8 pin or not? … [Read more...] about 9900k plus 8 pin CPU connector.
YouTuber unsurprisingly discovers that if you try to bend an iPad Pro, it will actually break
Editorial By William Gallagher Friday, November 16, 2018, 08:59 am PT (11:59 am ET) This just in: if you cut, scrape, burn, flex, and smash your iPad Pro there is a chance that it might break. This isn't what AppleInsider usually means by breaking news, but evidently, one YouTuber does.Breaking an iPad Pro to see if it breaks. (Credit: JerryRigEverything) YouTuberJerryRigEverything has smashed his iPad Pro so you don't have to. Only, you didn't have to. Still, thanks to this brave, brave man, it is now official —if you cut, scrape, burn, bend and smash your iPad Pro, it is conceivable that you might damage it. You have been warned. We had thought that AppleInsider testing was thorough but this does leave us behind —and we're fine with that. There's exhaustive testing and there is ridiculous, pointless testing with no scientific method or means behind it. For instance, at each single step in the process, this guy maintains that he's really checking out whether Apple is … [Read more...] about YouTuber unsurprisingly discovers that if you try to bend an iPad Pro, it will actually break
The best smartwatches and fitness trackers to give as gifts
That said, Fossil's Q Venture HR is a decent Wear OS alternative to the Galaxy Watch, with heart rate tracking and NFC connectivity. It could be as much as $100 cheaper, too, depending on the model you choose. Yet another option is Withing's Steel HR Sport -- it's not quite as smart as its rivals, but it makes up for the lack of high-tech touches with a timeless design and some solid fitness tracking features.Finally, if you're shopping for someone who's floated the idea of a Fitbit (or something like it), the brand's Versa smartwatch could be a great choice. It looks like a slightly wider Apple Watch with a battery rated for days of usage. Sure, it lacks GPS and NFC, but it comes with a number of health-related tracking features, including one that can monitor a woman's menstrual cycle. … [Read more...] about The best smartwatches and fitness trackers to give as gifts